Browsing: RFdiffusion

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Baker Lab Designs AI Proteases That Cleave Disease-Linked Proteins

Two teams at the University of Washington’s Institute for Protein Design published papers in Nature on October 14, 2026, reporting proteases designed from scratch with computational methods that hydrolyse the polypeptide backbone at chosen sequences, including sites in the human disease-associated proteins TDP-43, amyloid-β and serum amyloid A.